2003 Publications

Boren J, Lee WN, Bassilian S, Centelles JJ, Lim S, Ahmed S, Boros LG, Cascante M.
The stable isotope-based dynamic metabolic profile of butyrate-induced HT29 cell differentiation.
J Biol Chem. 2003 Aug 1;278(31):28395-402. Epub 2003 May 15.

Boros LG, Steinkamp MP, Fleming JC, Lee WN, Cascante M, Neufeld EJ.
Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA).
Blood. 2003 Nov 15;102(10):3556-61. Epub 2003 Jul 31.

Büechler P, Gukovskaya AS, Mouria M, Buchler MC, Buchler MW, Friess H, Pandol SJ, Reber HA, Hines OJ.
Prevention of metastatic pancreatic cancer growth in vivo by induction of apoptosis with genistein, a naturally occurring isoflavonoid.
Pancreas 26:264-273, 2003.

Go VL, Wang Y, Yang H, Lee WN.
Neuro-hormonal integration of metabolism: challenges and opportunities in the postgenomic era.
Nestle Nutr Workshop Ser Clin Perform Programme. 2004;(9):227-38; discussion. 238-42.

Gukovsky I, Reyes CN, Vaquero EC, Gukovskaya AS, Pandol SJ.
Curcumin ameliorates ethanol and non-ethanol experimental pancreatitis.
Am J Physiol Gastrointest Liver Physiol 28:G85-95. 2003

Gukovskaya AS, Vaquero EC, Edderkaoui M, Pandol SJ.
“Survival signals in pancreatic cancer.”
11th International Conference on Ulcer Research-ICUR, p. 345, 2003.

Henning SM, Fajardo-Lira C, Lee HW, Youssefian AA, Go VL, Heber D.
Catechin content of 18 teas and a green tea extract supplement correlates with the antioxidant capacity.
Nutr Cancer. 2003;45(2):226-35.

Huerta S, Irwin RW, Heber D, Go VL, Moatamed F, Huerta S, Ou C, Harris DM.
Intestinal polyp formation in the Apcmin mouse: effects of levels of dietary calcium and altered vitamin D homeostasis.
Dig Dis Sci. 2003 May;48(5):870-6.

Hwang IK, Go VL, Harris DM, Yip I, Kang KW, Song MK.
Effects of cyclo (his-pro) plus zinc on glucose metabolism in genetically diabetic obese mice.
Diabetes Obes Metab. 2003 Sep;5(5):317-24.

Lu S, Gukovsky I, Lugea A, Reyes CN, Huang ZZ, Chen L, Mato JM, Bottiglieri T, Pandol SJ.
Role of S-adenosylmethionine in two experimental models of pancreatitis.
FASEB J 17:56-8, 2003.

Lugea A, Gukovsky I, Gukovskaya AS, Pandol SJ.
Nonoxidative ethanol metabolites alter extracellular matrix protein content in rat pancreas.
Gastroenterology 125:1845-1859, 2003.

Marin S, Chiang K, Bassilian S, Lee WN, Boros LG, Fernandez-Novell JM, Centelles JJ, Medrano A, Rodriguez-Gil JE, Cascante M.
Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization.
FEBS Lett. 2003 Nov 20;554(3):342-6.

Pandol SJ, Gukovsky I, Satoh A, Fischer L, Lugea A, Gukovskaya AS.
“Molecular mechanisms of pancreatitis.”
11th International Conference on Ulcer Research-ICUR, p. 349, 2003.

Pandol SJ, Gukovsky I, Satoh A, Lugea A, Gukovskaya AS.
Animal Models of Alcoholic Pancreatitis: Role of Cholecystokinin.
Pancreas, 27:297-300, 2003.

Pandol SJ, Gukovsky I, Satoh A, Lugea A, Gukovskaya AS.
Emerging concepts for the mechanism of alcoholic pancreatitis from experimental models.
Journal of Gastroenterology, 38:623-628, 2003.

Song MK, Hwang IK, Rosenthal MJ, Harris DM, Yamaguchi DT, Yip I, Go VL.
Antidiabetic actions of arachidonic acid and zinc in genetically diabetic Goto-Kakizaki rats.
Metabolism. 2003 Jan;52(1):7-12.

Vaquero EC, Edderkaoui M, Nam KJ, Gukovsky I, Pandol SJ, Gukovskaya AS.
Extracellular matrix proteins protect pancreatic cancer cells from death via mitochondrial and nonmitochondrial pathways.
Gastroenterology 125:1188-202, 2003.

NCCAM Competing Renewal Submitted on September 12, 2012

Posted by PDC on Dec 7, 2012 in Home Feature, News | 0 comments

9th Annual Agi Hirshberg Symposium on Pancreatic Cancer. January 26, 2013

Posted by PDC on Dec 7, 2012 in Home Feature, News | 0 comments

Saturday, January 26, 2013 9:30 a.m. – 2:30 p.m. UCLA Faculty Center PROGRAM SCHEDULE FOR PATIENT AND FAMILY SESSION ADVANCES IN PANCREATIC CANCER MANAGEMENT 9:30 – 9:45 a.m. Welcome and Opening Remarks Agi Hirshberg Founder & CEO Hirshberg Foundation for Pancreatic Cancer Research 9:45 – 10:00 a.m. Remarks from the Dean of Medical School A. Eugene Washington, MD, MSc Vice Chancellor, Health Sciences & Dean, School of Medicine 10:00 – 10:30 a.m. ...

Inhibition of Glycogen Phosphorylation Induces Changes in Cellular Proteom and Signaling Pathways in MIA Pancreatic Cancer Cells

Posted by Sydney on Mar 28, 2012 in 2012 publications, Home Feature | 0 comments

Objectives: Novel quantitative proteomic approaches were used to study the effects of inhibition of glycogen phosphorylase on proteome and signaling pathways in MIA PaCa-2 pancreatic cancer cells. Methods: We performed quantitative proteomic analysis in MIA PaCa-2 cancer cells treated with a stratified dose of CP-320626 (5-chloro-1H-indole-2-carboxylic acid [1-(4-fuorobenzyl)-2-(4-hydroxypiperidin-1-yl)-2 oxoethyl] amide) (25, 50, and 100 μM). The effect of metabolic inhibition on cellular protein turnover dynamics was also studied using the...

8th Annual Agi Hirshberg Symposium on Pancreatic Cancer. January 31, 2012

Posted by Sydney on Mar 28, 2012 in Home Feature, News | 0 comments

JANUARY 31, 2012 This year’s meeting was held at the UCLA Faculty Center on January 31, 2012 with the support of the unrestricted educational grants from Amgen, Genetech and Celgene. We had participants from regional and national scientists and physicians as well as patients and family support groups. The meeting was opened by Ms. Agi Hirshberg, CEO and founder of the Hirshberg Foundation, by reviewing the accomplishments of the Foundation in research, patient care, and education over their fifteen year history. She highlighted the...