2010 Publications
Cao R, Zhang H, Lee WN, Deng C, Zhao Y, Go VL, Xiao J, Lappe J, Recker R, Yen Y, Wang Q, Tsai MY, Xiao GG.
Oxythiamine inhibits specific heat shock protein 27 (Hsp27) phosphorylation and cell proliferation in MIA pancreatic cancer cells.
J Proteome Res. 2010 February 5; 9(2): 980–989.
Vaitheesvaran B, Chueh FY, Xu J, Trujillo C, Saad MF, Lee WN, McGuinness OP, Kurland IJ.
Advantages of dynamic “closed loop” stable isotope flux phenotyping over static “open loop” clamps in detecting silent genetic and dietary phenotypes.
Metabolomics. 2010:180-190. PMID: 20445758 [PubMed]PMCID: PMC2862950
Alcarraz-Vizán G, Boren J, Lee WN, Cascante M.
Histone deacetylase inhibition results in a common metabolic profile associated with HT29 differentiation.
Metabolomics. 2010:229-237. PMID: 20445757 [PubMed] PMCID: PMC2862949
Xiao J, Lee WN, Zhao Y, Cao R, Go VL, Recker RR, Wang Q, Xiao GG.
Profiling pancreatic cancer-secreted proteome using 15N amino acids and serum-free media.
Pancreas. 2010 Jan;39(1):e17-23. PMID: 19904223; PMC2835986
Zhang H, Cao R, Lee WN, Deng C, Zhao Y, Lappe J, Recker R, Yen Y, Wang Q, Tsai MY, Go VL, Xiao GG.
Inhibition of protein phosphorylation in MIA pancreatic cancer cells: confluence of metabolic and signaling pathways.
J Proteome Res. 2010 Feb 5;9(2):980-9. PMID: 20035555; PMC2836017
Lee, WN, Wahjudi PN, Xu, J, Go VLW.
Tracer-based Metabolomics: Concepts and Practices.
Clin Biochem. 2010 Nov;43(16-17):1269-77. Epub 2010 Aug 14. PubMed PMID: 20713038; PubMed Central PMCID: PMC2952699.
Byerley LO and Lee WN.
Are ethanol and fructose similar?
J Am Diet Assoc. 2010 Sep;110(9):1300-1.
Sinha-Hikim I, Shen R, Lee WN, Crum A, Vaziri ND, Norris KC.
Effects of a novel cystine based glutathione precursor on oxidative stress in vascular smooth muscle cells.
Am J Physiol Cell Physiol. 2010 Sep;299(3):C638-42. PMID: 20592243 [PubMed - indexed for MEDLINE] PMCID: PMC2944321
Liu PY, Erkkila K, Lue Y, Jentsch JD, Schwarcz MD, Abuyounes D, Sinha Hikim AP, Wang C, Lee PW, Swerdloff RS.
Genetic, Hormonal and metabolomic influences on social behavior and gender preference of XXY mice.
Am J Physiol Endocrinol Metab. 2010 Sep;299(3):E446-55. Epub 2010 Jun 22. PMID: 20570823 [PubMed - indexed for MEDLINE]
Selivanov VA, Vizán P, Mollinedo F, Fan TW, Lee PW, Cascante M.
Edelfosine-induced metabolic changes in cancer cells that precede the overproduction of reactive oxygen species and apoptosis.
BMC Syst Biol. 2010 Oct 6;4:135. PMID: 20925932 [PubMed - indexed for MEDLINE] Free PMC Article
I.Ohno, G.Eibl, I.Odinokova, M.Edderkaoui, R.D.Damoiseaux, M.Yazbec, R.Abrol, W.A.Goddard,III, O.Yokosuka, S.J.Pandol, A.S.Gukovskaya.
Rottlerin stimulates apoptosis in pancreatic cancer cells through interactions with proteins of the bcl-2 family.
Am J Physiol Gastrointest Liver Physiol 2010;298:G63-G73 (PMCID: PMC2806098)
H.Pham, M.Chen, A.Li, J.King, E.Angst, D.W.Dawson, J.Park, H.A.Reber, O.J.Hines, G.Eibl.
Loss of 15-Hydroxyprostaglandin Dehydrogenase Increases Prostaglandin E2 in Pancreatic Tumors.
Pancreas 2010;39:332-339 (PMCID: PMC2859226)
E.Angst, D.W.Dawson, A.Nguyen, J.Park, V.L.W.Go, H.A.Reber, O.J.Hines, G.Eibl.
Epigenetic regulation affects N-myc downstream regulated gene-1 expression indirectly in pancreatic cancer cells.
Pancreas. 2010 Jul;39(5):675-9.
E.Angst, M.Chen, M.Mojadidi, O.J.Hines, H.A.Reber, G.Eibl.
Bioluminescence Imaging of Angiogenesis in a Murine Orthotopic Pancreatic Cancer Model.
Mol Imaging Biol. 2010 Dec;12(6):570-5.
L.Zhang, E.Angst, J.Park, A.Moro, D.Dawson, H.Reber, G.Eibl, J.Hines, V.-L.Go, Q.-Y.Lu.
Quercetin aglycone is bioavailable in murine pancreas and pancreatic xenografts.
J Agric Food Chem 2010;58:7252-7257 (PMCID: PMC2894579)
T.R.Donahue, O.J.Hines, J.J.Farrell, J.S.Tomlinson, G.Eibl, H.A.Reber.
Cystic neoplasms of the pancreas. Results from 114 cases.
Pancreas 2010 Nov;39(8):1271-1276 (PMCID in progress)
E.Angst, D.W.Dawson, D.Stroka, B.Gloor, J.Park, D.Candinas, H.A.Reber, O.J.Hines, G.Eibl.
N-myc downstream regulated gene-1 expression correlates with reduced pancreatic cancer growth and increased apoptosis in vitro and in vivo.
Surgery 2011;149(5):614-624 (PMCID in progress)
A.Li, X.J.Cheng, A.Moro, R.K.Singh, O.J.Hines, G.Eibl.
CXCR2-dependent endothelial progenitor cell mobilization in pancreatic cancer growth.
Transl Oncol 2011;4(1):20-28 (PMCID: PMC3026405)
H.Takahashi, A.Li, D.W.Dawson, O.J.Hines, H.A.Reber, G.Eibl.
Cyclooxygenase-2 confers growth advantage to syngeneic pancreatic cancer cells.
Pancreas 2011;40(3):453-459 (PMCID: PMC3077942)
A.Li, J.King, A.Moro, M.D.Sugi, D.W.Dawson, J.Kaplan, G.Li, X.Lu, R.M.Strieter, M.Burdick, V.L.Go, H.A.Reber, G.Eibl, O.J.Hines.
Overexpression of CXCL5 is associated with poor survival in patients with pancreatic cancer.
Am J Pathol 2011;178(3):1340-1349 (PMCID: PMC3069811)
H. Zhang, R. Cao, W.N.P. Lee, C. Deng, Y. Zhao, J. Lappe, R. Recker, Y. Yen, Q. Wang, M.Y. Tsai, V.L.W. Go, and G.G. Xiao.
Inhibition of Protein Phosphorylation in MIA Pancreatic Cancer Cells: Confluence of Metabolic and Signaling Pathways.
J Proteome Res. 2010 Feb 5;9(2):980-9. PMID: 20035555; PMC2836017
Mao JT, Nie WX, Tsu IH, Jin YS, Rao JY, Lu QY, Zhang ZF, Go VLW, Serio KJ.
White Tea Extract Induces Apoptosis in Nonsmall Cell Lung Cancer Cells–the Role of PPAR-and 15-Lipoxygenase.
Cancer Prevention Research. 2010 Sep;3(9):1132-40.
J.C. King, A. Li, H.A. Reber, V.L.W. Go, G. Eibl, O.J. Hines.
Apigenin induces pancreatic cancer cell apoptosis by a p53-mediated mechanism.
J Surg Res 2010;158(2):393
Pandol SJ, Gorelick FS, Gerloff A, Lugea A.
Alcohol abuse, endoplasmic reticulum stress and pancreatitis.
Dig Dis. 2010;28(6):776-82
Lugea A, Gong J, Nguyen J, Nieto J, French SW, Pandol SJ.
Cholinergic Mediation of Alcohol-Induced Experimental Pancreatitis.
Alcohol Clin Exp Res. 2010; 34:1768-81. PMC2950903
Ohno I, Eibl G, Odinokova I, Edderkaoui M, Damoiseaux RD, Yazbec M, Abrol R, Goddard WA III, Pandol SJ, Gukovskaya AS.
Rottlerin Stimulates Apoptosis in Pancreatic Cancer Cells Through Interactions Between Proteins of The Bcl-2 Family.
Am J Physiol Gastrointest Liver Physiol. 2010 Jan;298(1):G63-73. PMID: 19762434
Pandol SJ, Gorelick FS, Gerloff A, Lugea A.
Alcohol abuse, endoplasmic reticulum stress and pancreatitis.
Dig Dis. 2010;28(6):776-82. Epub 2011 Apr 27. PMCID: PMC3211518
Lugea A, Gong J, Nguyen J, Nieto J, French SW, Pandol SJ.
Cholinergic Mediation of Alcohol-Induced Experimental Pancreatitis.
Alcohol Clin Exp Res 2010; 34:1768-81. PMC2950903